Problem Set "One Compartment Model with i.v. Injection Only Urinary Elimination
A 70 kg patient was given a bolus i.v. injection of 1000 mg of a drug. The drug is not bound to plasma proteins and is excreted unchanged solely into the urine. When the plasma concentration (Cp) was assayed, the following data was obtained.
1. Plot the plasma data on linear coordinate paper and estimate t1/2 and Vd.
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